Surgery for Obesity and Related Diseases
Volume 6, Issue 1 , Pages 36-40 , January 2010

Peroral endoscopic anastomotic reduction improves intractable dumping syndrome in Roux-en-Y gastric bypass patients

  • Gloria Fernández-Esparrach, M.D., Ph.D.

      Affiliations

    • Department of Medicine, Division of Gastroenterology, Brigham and Women's Hospital, Boston, Massachusetts
    • ,
  • David B. Lautz, M.D.

      Affiliations

    • Department of Surgery, Division of General and Gastrointestinal Surgery, Brigham and Women's Hospital, Boston, Massachusetts
    • ,
  • Christopher C. Thompson, M.D., M.Sc., F.A.C.G., F.A.S.G.E.

      Affiliations

    • Department of Medicine, Division of Gastroenterology, Brigham and Women's Hospital, Boston, Massachusetts
    • Corresponding Author InformationReprint requests: Christopher C. Thompson, MD, MSc, FACG, FASGE, Division of Developmental Endoscopy, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115

Received 27 September 2008 ,Revised 6 April 2009 ,Accepted 8 April 2009.

References 

  1. Santry HP, Gillen DL, Lauderdale DS. Trends in bariatric surgical procedures. JAMA. 2005;294:1909–1917
  2. Buhl K, Schlag P, Herfath C. Quality of life and functional results following different types of resection for gastric carcinoma. Eur J Surg Oncol. 1990;16:404–409
  3. Fujioka K. Follow-up of nutritional and metabolic problems after bariatric surgery. Diabetes Care. 2005;28:481–484
  4. Hopman WP, Wolberink RG, Lamers CB, Van Tongeren JH. Treatment of the dumping syndrome with the somatostatin analogue SMS 201-995. Ann Surg. 1988;207:155–159
  5. Hobsley M. Dumping and diarrhea. Br J Surg. 1981;68:681–684
  6. Thompson C, Carr-Locke D, Saltzman J, Lautz D, Robinson M. Peroral endoscopic repair of staple-line dehiscences in Roux-en-Y gastric bypass: a less invasive approach. (abstract) Gastrointest Endosc. 2004;126(Suppl 2):A810
  7. Thompson CC, Slattery J, Bundga ME, Lautz DB. Peroral endoscopic reduction of dilated gastrojejunal anastomosis after Roux-en-Y gastric bypass: a possible new option for patients with weight regain. Surg Endosc. 2006;20:1744–1748
  8. Brolin RE. Update: NIH consensus conference (Gastrointestinal surgery for severe obesity). Nutrition. 1996;12:403–404
  9. Schauer PR, Ikramuddin S, Gourash W, et al. Outcomes after laparoscopic gastric Roux-en-Y gastric bypass for morbid obesity. Ann Surg. 2000;232:515–529
  10. Mun EC, Blackburn GL, Matthews JB. Current status of medical and surgical therapy for obesity. Gastroenterology. 2001;120:669–681
  11. Ralphs DNL, Thompson JPS, Haynes S, Lawson-Smith C, Hobsley M, Le Quesne LP. The relationship between the rate of gastric emptying and the dumping syndrome. Br J Surg. 1978;65:637–641
  12. Carvajal SH, Mulvihill SJ. Postgastrectomy syndromes: dumping and diarrhea. Gastroenterol Clin North Am. 1994;23:261–279
  13. Thompson C, Carr-Locke D. Novel endoscopic approaches to common bariatric postoperative complications. Presented at: Digestive Disease Week, ASGE Video Forum; May 15–20, 2004; New Orleans, La.
  14. Schweitzer M. Endoscopic intraluminal suture plication of the gastric pouch and stoma in postoperative Roux-en-Y gastric bypass patients. J Laparoendosc Adv Surg Tech A. 2004;14:223–226
  15. Filipi CJ, Lehman GA, Rothstein RI, et al. Transoral, flexible endoscopic suturing for treatment of GERD: a multicenter trial. Gastrointest Endosc. 2001;53:416–422
  16. Mahmood Z, McMahon BP, Arfin Q, et al. EndoCinch therapy for gastroesophageal reflux disease: a one-year prospective follow-up. Gut. 2003;52:34–39
  17. Pai RD, Doktor V, Lautz DB, Thompson CC. Peroral endoscopic repair of fistulae in Roux-en-Y gastric bypass patients: a clinical experience in 25 patients. Gastroenterology. 2007;132:A79
  18. Herron DM, Birkett DH, Thompson CC, Bessler M, Swanstrom LL. Gastric bypass pouch and stoma reduction using a transoral endoscopic anchor placement system: a feasibility study. Surg Endosc. 2008;22:1093–1099
  19. Mullady DK, Lautz DB, Thompson CC. Treatment of weight regain following gastric bypass surgery using a novel endoscopic device: technical feasibility and early outcomes in twenty patients. Presented at: Digestive Disease Week, ASGE Video Forum; May 17–22, 2008; San Diego, Ca.
  20. Overcash WT. Natural orifice surgery (NOS) using StomaphyX™ for repair of gastric leaks after bariatric revisions. Obes Surg. 2008;18:882–885

 G. Fernández-Esparrach is currently at Hospital Clínic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIPAPS), Centro de Investigación Biomédica en Red en el Área temática de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain.

PII: S1550-7289(09)00362-1

doi: 10.1016/j.soard.2009.04.002

Surgery for Obesity and Related Diseases
Volume 6, Issue 1 , Pages 36-40 , January 2010

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