Abstract
Background
Laparoscopic sleeve gastrectomy (SG) is a validated procedure for the surgical treatment
of morbid obesity. Cirrhosis is often considered a relative contraindication to elective
extrahepatic surgery. The objective of this study was to evaluate the morbidity related
to SG performed in cirrhotic patients compared with noncirrhotic patients.
Methods
Between March 2004 and January 2013, we included all patients with cirrhosis undergoing
SG (13 patients). These patients (SG-cirrhosis group) were matched in terms of preoperative
data (age, gender, body mass index, and co-morbidities) on a 1:2 basis, with 26 noncirrhotic
patients (SG group) selected from a population of 750 patients. Cirrhosis was diagnosed
postoperatively on histologic exam. The primary endpoint was the overall postoperative
complication rate. Secondary endpoints were operating time, revisional surgery rate,
gastric fistula and bleeding rates, postoperative mortality, and weight loss over
a 24-month period.
Results
The SG-cirrhosis group consisted of 13 patients with a median age of 52 years. All
patients in the SG-cirrhosis group were Child A. Etiology of cirrhosis was related
to NASH in 93.3%. Median operating time in the SG-cirrhosis group and SG group was
75 minutes versus 80 minutes (P = .59). No postoperative mortality was observed in either group. The overall postoperative
complication rate was 7.7% versus 7.7% (P = 1). The major complication rate was 0% versus 7.7% (P = .22), and the postoperative gastric fistula rate was 0% versus 3.8% (P = .47). No complications related to cirrhosis were reported.
Conclusion
SG can be performed in Child A cirrhosis with no increased risk of postoperative complications
and no specific complications related to cirrhosis. Weight loss for patients with
cirrhosis undergoing SG is similar to that observed in noncirrhotic patients.
Keywords
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References
- Nationwide volume and mortality after elective surgery in cirrhotic patients.J Am Coll Surg. 2009; 208: 96-103
- Morbidity and mortality in cirrhotic patients undergoing anesthesia and surgery.Anesthesiology. 1999; 90: 42-53
- Model for end-stage liver disease (MELD) and allocation of donor livers.Gastroenterology. 2003; 124: 91-96
- A metaanalysis of laparoscopic cholecystectomy in patients with cirrhosis.J Am Coll Surg. 2003; 197: 921-926
- Colorectal adenocarcinoma in cirrhotic patients.J Am Coll Surg. 2003; 196: 874-879
- Esophagogastrectomy for carcinoma in cirrhotic patients.Hepatogastroenterology. 1990; 37: 388-391
- Is there a place for esogastric cancer surgery in cirrhotic patients?.Ann Surg Oncol. 2008; 15: 680-682
- Cirrhosis should not be considered as an absolute contraindication for pancreatoduodenectomy.Hepatogastroenterology. 2012; 59: 881-883
- Is bariatric surgery safe in cirrhotics?.Hepat Mon. 2013; 13: e8536
- Nonalcoholic steatohepatitis (NASH) does not increase complications after laparoscopic bariatric surgery.Obes Surg. 2011; 21: 1714-1720
- Laparoscopic bariatric surgery improves candidacy in morbidly obese patients awaiting transplantation.Surg Obes Relat Dis. 2008; 4 (discussion 164–5): 159-164
- Bariatric surgery in patients with liver cirrhosis.Surg Obes Relat Dis. 2013; 9: 1-6
Gastrectomie Longitudinale [sleeve gastrectomy] pour obésité. Hautes autorité de la santé. Recommandations 2008 www.has-sante.fr
- Technique de la gastrectomie longitudinale (sleeve gastrectomy) par laparoscopie.EMC (Elsevier Masson SAS, Paris), Techniques chirurgicales—Appareil digestif. 2011; : 40-385
- The morphology of cirrhosis. Recommendations on definition, nomenclature, and classification by a working group sponsored by the World Health Organization.J Clin Pathol. 1978; 31: 395-414
- Surgery and portal hypertension.Major Probl Clin Surg. 1964; 1: 1-85
- Transection of the oesophagus for bleeding oesophageal varices.Br J Surg. 1973; 60: 646-649
- Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey.Ann Surg. 2004; 240: 205-213
- Recommendations for reporting weight loss.Obes Surg. 2003; 13: 159-160
- Nonalcoholic fatty liver disease.N Engl J Med. 2002; 346: 1221-1231
- Liver abnormalities in severely obese subjects: effect of drastic weight loss after gastroplasty.Int J Obes Relat Metab Disord. 1998; 22: 222-226
- Roux-en-Y gastric bypass improves the nonalcoholic steatohepatitis (NASH) of morbid obesity.Obes Surg. 2006; 16: 270-278
- Duodenal switch has no detrimental effects on hepatic function and improves hepatic steatohepatitis after 6 months.Obes Surg. 2005; 15: 1418-1423
- Effects of bariatric surgery on nonalcoholic fatty liver disease: preliminary findings after 2 years.J Gastroenterol Hepatol. 2007; 22: 510-514
- Seven hundred forty-seven hepatectomies in the 1990s: an update to evaluate the actual risk of liver resection.J Am Coll Surg. 2000; 191: 38-46
- Laparoscopic cholecystectomy and cirrhosis: a case-control study of outcomes.Liver Transpl. 2000; 6: 340-344
- Sleeve gastrectomy and the risk of leak: a systematic analysis of 4,888 patients.Surg Endosc. 2012; 26: 1509-1515
- Combined liver transplantation and gastric sleeve resection for patients with medically complicated obesity and end-stage liver disease.Am J Transplant. 2013; 13: 363-368
- Safety and feasibility of sleeve gastrectomy in morbidly obese patients following liver transplantation.Surg Endosc. 2013; 27: 81-85
Article info
Publication history
Published online: October 03, 2013
Accepted:
September 27,
2013
Received:
August 8,
2013
Identification
Copyright
© 2014 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.