Abstract
Background
Obesity is a risk factor for the development of gout. An increased incidence of early
gouty attacks after bariatric surgery has been reported, but the data is sparse. The
effect of weight loss surgery on the behavior of gout beyond the immediate postoperative
phase remains unclear. The objective of this study was to evaluate the pre- and postoperative
frequency and features of gouty attacks in bariatric surgery patients.
Methods
Charts were reviewed to identify patients who had gout before bariatric surgery. Demographic
and gout-related parameters were recorded. The comparison group consisted of obese
individuals with gout who underwent nonbariatric upper abdominal procedures.
Results
Ninety-nine morbidly obese patients who underwent bariatric surgery had gout. The
comparison group consisted of 56 patients. The incidence of early gouty attack in
the first month after surgery was significantly higher in the bariatric group than
the nonbariatric group (17.5% versus 1.8%, P = .003). In the bariatric group, 23.8% of patients had at least one gouty attack
during the 12-month period before surgery, which dropped to 8.0% during postoperative
months 1–13 (P = .005). There was no significant difference in the number of gouty attacks in the
comparison group before and after surgery (18.2% versus 11.1%, P = .33). There was a significant reduction in uric acid levels 13-months after bariatric
surgery compared with baseline values (9.1±2.0 versus 5.6±2.5 mg/dL, P = .007).
Conclusion
The frequency of early postoperative gout attacks after bariatric surgery is significantly
higher than that of patients undergoing other procedures. However, the incidence decreases
significantly after the first postoperative month up to 1 year.
Keywords
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Article info
Publication history
Published online: March 03, 2014
Accepted:
February 20,
2014
Received:
January 9,
2014
Footnotes
☆This study has been presented at ASMBS Obesity Week 2013, November 11-16, Georgia World Congress, Atlanta, GA.
Identification
Copyright
© 2014 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.
