Early effects of sleeve gastrectomy on rheumatoid arthritis

      The significant impact of obesity on the musculoskeletal system is associated with osteoarthritis (OA). Rheumatoid arthritis (RA) is an autoimmune disease that typically affects the small joints. A low grade inflammatory state related to obesity may play a role in OA and are also culprits in RA. There is some evidence that sleeve gastrectomy ameliorates chronic inflammation related to obesity through weight loss. It has been reported that in patients with RA who underwent bariatric surgery, significant weight loss was associated with improvement in disease activity, reductions in medication use, and a reduction in inflammatory markers. This time, we report the early effects of sleeve gastrectomy on a morbidly obese japanese female who had severe RA.
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