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Is the intestinal microbiome a modifiable cofactor in the development of hyperoxaluria after Roux-en-Y gastric bypass?

      Patients with enteric hyperoxaluria hyperabsorb oxalate from their diet. In healthy individuals, only a minority of ingested oxalate is absorbed (~10%). However, this percentage increases to 10%–30% among patients with enteric hyperoxaluria [
      • Hesse A.
      • Schneeberger W.
      • Engfeld S.
      • Von Unruh G.E.
      • Sauerbruch T.
      Intestinal hyperabsorption in calcium oxlate stone formers: application of a new test with [13 C2] oxalate.
      ]. Known and modifiable determinants of oxalate absorption from the diet include the absolute and relative amounts of oxalate, fat, and calcium eaten.
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