Adolescent obesity is a significant factor in caring for patients with developmental
delay (DD). Sleeve gastrectomy provides durable weight loss for teens with obesity
but requires behavioral change that may not occur in patients with DD.
To determine whether patients with DD had similar weight loss and adverse outcomes
to patients without a diagnosis of DD after sleeve gastrectomy.
Academic children's hospital, United States.
Patients with DD undergoing sleeve gastrectomy were matched to adolescents without
DD. Chart review was performed to determine etiology and severity of DD, weight, and
body mass index (BMI) change in each group at 3, 6, 9, and 12 months postoperatively.
One-year emergency department visits, readmissions, and reoperations were reviewed.
Ten patients with DD and 44 patients without DD underwent sleeve gastrectomy between
2008 and 2017. Six patients with DD (60%) had mild cognitive impairment, 3 patients
(30%) had moderate cognitive impairment, and 1 patient (10%) had severe cognitive
impairment. Patients were 81.5% female, had a mean age of 17.3 years, and had a preoperative
BMI of 48.6 kg/m2. Preoperative BMI was similar in the 2 groups, and percent BMI reduction at 1 year
was −29% (95% confidence interval: −35 to −23) and −26% (95% confidence interval:
−29 to −23) in groups with and without DD respectively (group by time interaction,
P = .27).
Adolescents with DD experience similar 1-year weight loss and adverse events following
sleeve gastrectomy to adolescents without DD. Understanding the long-term outcomes
for this population is crucial to ensure appropriate implementation of surgical weight