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Deficits in cognitive control during alcohol consumption after bariatric surgery

Published:October 27, 2022DOI:https://doi.org/10.1016/j.soard.2022.10.014

      Highlights

      • Bariatric surgery patients completed cognitive tasks following alcohol consumption
      • Most cognitive task performance improved over time, likely due to practice effects
      • Number of commission errors post-surgery was impacted by baseline cognitive control

      Abstract

      Background

      While bariatric surgery results in substantial weight loss, one negative side effect of surgery is that patients often experience more rapid and intense intoxication effects after consuming alcohol.

      Objectives

      Given that alcohol use has been associated with impaired cognitive functioning in the general population, this study examined whether acute alcohol consumption after bariatric surgery immediately led to impaired cognitive control, and whether this effect was impacted by baseline levels of cognitive control.

      Setting

      Nonprofit teaching hospital, United States.

      Methods

      Participants were 34 adults who attended a laboratory visit before and 1 year after Roux-en-Y gastric bypass surgery, wherein they consumed a weight-based dose of alcohol and completed cognitive testing over the course of 3 hours.

      Results

      A series of generalized mixed-effect models demonstrated that performance on the cognitive task generally improved over time, likely due to practice effects. However, following bariatric surgery, individuals with impaired cognitive control before consuming alcohol experienced greater commission errors immediately afterward.

      Conclusions

      These findings suggest that alcohol use after bariatric surgery may produce immediate deficits in inhibitory control among individuals who are already vulnerable to impaired cognitive control. Clinicians should seek to educate bariatric surgery candidates on this possible effect, as deficits in inhibitory control may ultimately lead to risky behaviors and poor adherence with postsurgical medical recommendations.

      Keywords

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