Rheumatic disease represents a broad spectrum of syndromes with varying ailments and
symptoms working through proinflammatory states. In rheumatoid arthritis, inflammatory
changes in synovial membranes leads to musculoskeletal pain and dysfunction, in addition
to developing other disorders including cardiovascular and respiratory diseases [
[1]
]. There is no cure for rheumatic diseases, with a goal to limit symptoms and end-organ
damage. First-line therapies for these diseases include medication treatments aimed
at diminishing this overactivity. Obesity is also a proinflammatory state, and the
worldwide epidemic of obesity has resulted in increasing numbers of patients being
at risk. Through adipose-derived inflammation, obesity likely contributes to the development,
progression, and ultimately worsening of rheumatologic diseases [
[2]
].To read this article in full you will need to make a payment
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References
- The etiology of rheumatoid arthritis.J Autoimmun. 2020; 110: 02400
- Consequences of bariatric surgery on outcomes in rheumatic diseases.Arthritis Res Ther. 2019; 21: 83
- Effect of metabolic surgery on immunosuppressive medication use in patients with rheumatic diseases.Surg Obes Relat Dis. Epub 2022 Sep 6;
Article Info
Publication History
Published online: November 15, 2022
Publication stage
In Press Journal Pre-ProofIdentification
Copyright
© 2022 American Society for Metabolic and Bariatric Surgery. Published by Elsevier Inc. All rights reserved.
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- Effect of metabolic surgery on immunosuppressive medication use in patients with rheumatic diseasesSurgery for Obesity and Related Diseases
