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Bariatric surgery and cardiovascular outcomes: it’s time to do a randomized trial

Published:January 02, 2023DOI:https://doi.org/10.1016/j.soard.2022.12.037
      Obesity is a common diagnosis among heart failure patients and is present in a majority of those with preserved ejection fraction [
      • Powell-Wiley T.M.
      • Poirier P.
      • Burke L.E.
      • et al.
      Obesity and cardiovascular disease: a scientific statement from the American Heart Association.
      ]. Severe obesity promotes heart failure through its association with several cardiovascular risk factors, including type 2 diabetes, dyslipidemia, sleep apnea, and systemic hypertension. Besides obesity-associated cardiovascular risk factors, obesity, particularly severe obesity, induces a variety of adaptations/alterations in cardiac structure and function that may progressively lead to the development of heart failure. Additionally, several metabolic, inflammatory, and neurohormonal changes associated with severe obesity may contribute with impairment of the cardiovascular system.
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